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For anyone interested in the spread of information among a human population, it is important to understand whether there are individuals who exert more impact on the knowledge, perceptions, and behavior than others. Social scientists interested in the causes of social change can find root causes in the existence, number, and behavior of influentials. The rapidly growing number of researchers interested in social networks can add another explanatory variable to the array of “physical” constraints of network structures. For marketers, politicians, and activists interested in actionable strategies, targeting influentials could increase the efficiency of their campaigns.